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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name CRNDE
ncRNA Category lncRNA
ID 643911
Ensembl ENSG00000245694
Synonyms CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM samples, blood
Methods Whole genome sequencing, SNP array, microarray, RNA-seq
Expression pattern associated
Functional description SF3B1 is recurrently mutated in uveal melanoma, and the mutations are associated with differential alternative splicing of protein coding genes, including ABCC5 and UQCC, and of the long noncoding RNA CRNDE.
PubMed ID 23861464
Year 2013
Title SF3B1 mutations are associated with alternative splicing in uveal melanoma.
Drug-related ncRNA NO

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